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BillionToOne

Molecular diagnostics for cancer liquid biopsy and prenatal testing.

PublicMenlo Park, CAFounded 2015
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About

BillionToOne developed a molecular counting technique called QCT that increases cell-free DNA diagnostics resolution by over 1,000 fold. Its Northstar Select liquid biopsy test guides therapy for stage III and IV cancer patients, while Northstar Response tracks treatment response. The company IPO'd in November 2025 after growing from $0 to $125M ARR in four years.

Total Funding

$389M

Key Product

Northstar Select liquid biopsy test

Geography

North America

Key Investors

Premji InvestAdams Street PartnersHummingbird Ventures

Focus Areas

DiagnosticsEarly Detection / Screening

Technology

Liquid BiopsyGenomics / Sequencing

Cancer Types

Pan-cancer

Last updated: Feb 4, 2026

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